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ACUTE SPINAL CORD INJURY (E.G., IVDD OR FCE) Use alongside rest and conventional care

Results corresponded with disrupted myocardial redox balance found in heart tissues of PET MPs-treated mice, as evidenced by elevated malondialdehyde (MDA) levels and reduced antioxidant enzyme activity

This may be due to the effects of female hormones: estrogens increase cholesterol secretion into bile, and progesterone decreases gallbladder motility

Where clinical suspicion remains high despite a normal serum B12, additional markers may be requested, including: Holotranscobalamin (active B12) a more specific marker of B12 status, available in some UK laboratories as an alternative or confirmatory test [11] [12] Methylmalonic acid (MMA) elevated in functional B12 deficiency

Figure 1 Vitamin B12 deficiency, defined as ciculatory B12 level below 150200 pg/mL (borderline 200300 pg/mL) (8), is a significant global health concern, particularly affecting the elderly (9, 10), pregnant women (11), and young children (12), especially in regions with limited dietary options